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化学

何福生


 姓名:何福生,性别:男                    

学科专业:化学

学历及学位:研究生,博士

职称:教授

联系方式:Email: hefs@tzc.edu.cn

 

学习经历:

2012年毕业于江西师范大学,化学专业,获理学学士学位

2017年毕业于华东理工大学,药学专业,获医学博士学位

工作经历:

20177月至201712月,上海合全药物研发有限公司,高级研究员

20181月至201912月,浙江大学,博士后

20192月至今,台州学院,讲师、教授

研究方向:
   自由基化学;不对称催化;药物合成化学

主要科研项目:

主持国家自然科学基金项目浙江省自然科学基金项目和中国博士后科学基金面上项目等多项

近期代表性论文:

  1. Wu, Xianda; Zheng, Jiayi; He, Fu-Sheng*; Wu, Jie*. Ligand-Enabled Copper-Catalyzed Ullmann-Type S-C Bond Formation to Access Sulfilimines. Org. Lett. 2024, 26, 8200-8205.

  2. Wu, Xianda; Chen, Minghong; He, Fu-Sheng*; Wu, Jie*. Synthesis of functionalized sulfilimines via iron-catalyzed sulfur alkylation of sulfenamides with diazo compounds. Green. Chem. 2023, 25, 9092-9096.

  3. Wu, Xianda; Chen, Minghong; He, Fu-Sheng*; Wu, Jie*. Synthesis of Sulfilimines via Aryne and Cyclohexyne Intermediates. Org. Lett. 2023, 25, 5157-5161.

  4. He, Fu-Sheng; Zhang, Chun; Jiang, Minghui; Lou, Lujun; Wu, Jie; Ye, Shengqing. Access to chiral β-sulfonyl carbonyl compounds via photoinduced organocatalytic asymmetric radical sulfonylation with sulfur dioxide. Chem. Sci. 2022, 13, 8834-8839.

  5. He, Fu-Sheng*; Bao, Ping; Tang, Zhimei; Yu, Feiyan; Deng, Wei-Ping; Wu, Jie*. Photoredox-Catalyzed α-Sulfonylation of Ketones from Sulfur Dioxide and Thianthrenium Salts. Org. Lett. 2022, 24, 2955-2960.

  6. He, Fu-Sheng*; Su, Lingjing; Yu, Feiyan; Tang, Zhimei; Wu, Jie*. Construction of sulfonated spiro[5,5]trienones from sulfur dioxide via iron-catalyzed dearomative spirocyclization of biaryls. Org. Chem. Front. 2022, 9, 1937-1942.

  7. He, Fu-Sheng*; Bao, Ping; Yu, Feiyan; Zeng, Ling-Hui; Deng, Wei-Ping; Wu, Jie*. Copper-Catalyzed Regioselective 1,4-Selenosulfonylation of 1,3-Enynes to Access Cyanoalkylsulfonylated Allenes. Org. Lett. 2021, 23, 7472-7476.

  8. Cen, Xufen; Chen, Yanying; Xu, Xiaoyan; Wu, Ronghai; He, Fusheng; Zhao, Qingwei; Sun, Qiming; Yi, Cong; Wu, Jie*; Najafov, Ayaz;* Xia, Hongguang* Pharmacological targeting of MCL-1 promotes mitophagy and improves disease pathologies in an Alzheimer's disease mouse model. Nat. Commun. 2020, 11, 5731.

  9. Gong, Xinxing; Yang, Min; Liu, Jin-Biao; He, Fu-Sheng*; Fan, Xiaona*; Wu, Jie*. A metal-free route to alkynyl sulfones under photoinduced conditions with the insertion of sulfur dioxide. Green. Chem. 2020, 22, 1906-1910.

  10. He, Fu-Sheng; Ye, Shengqing; Wu, Jie*. Recent Advances in Pyridinium Salts as Radical Reservoirs in Organic Synthesis. ACS Catal. 2019, 9, 8943-8960.

    个人荣誉及获奖:

入选台州市高层次人才特支计划青年人才

2023-2024入选美国斯坦福大学发布的“全球前2%顶尖科学家榜单”

获台州市自然科学学术奖二等奖和三等奖各一项

获校青年英才、先进教师等荣誉或称号