姓名:章礼炜,性别:男
学科专业:骨科
学历及学位:研究生,博士
职称:主治医师
职务:无
联系方式:Email: medzlw@sina.com
学习经历:
2015年毕业于温州医科大学,获医学学士学位
2018年毕业于温州医科大学,获医学硕士学位
2021年毕业于苏州大学,获医学博士学位
工作经历:
2021年8月至今,浙江省台州医院骨外科
社会主要兼职:
无
研究方向:
肌骨代谢及相关退行性疾病病理机制、防治研究
主要科研项目:
目前主持国家自然科学基金青年科学基金项目、浙江省实验动物科技项目、台州市科技计划项目等
近期代表性论文及成果:
Zhang L, Fu X, Ni L, et al. Hedgehog Signaling Controls Bone Homeostasis by Regulating Osteogenic/Adipogenic Fate of Skeletal Stem/Progenitor Cells in Mice [J]. J Bone Miner Res, 2022, 37(3): 559-576.
Zhang L, Yang Y, Liao Z, et al. Genetic and pharmacological activation of Hedgehog signaling inhibits osteoclastogenesis and attenuates titanium particle-induced osteolysis partly through suppressing the JNK/c-Fos-NFATc1 cascade [J]. Theranostics, 2020, 10(15): 6638-6660.
Zhang L, Zhang L, You H, et al. Inhibition of osteoclastogenesis by histone deacetylase inhibitor Quisinostat protects mice against titanium particle-induced bone loss [J]. Eur J Pharmacol, 2021, 904: 174176.
Ma L, Zhang L, Liao Z, et al. Pharmacological inhibition of protein S-palmitoylation suppresses osteoclastogenesis and ameliorates ovariectomy-induced bone loss [J]. J Orthop Translat, 2023, 42: 1-14.
Xie C, Zhang L, Zhang D, et al. Efficacy and safety of vancomycin for local application in the prevention of surgical site infection after joint arthroplasty: a systematic review and meta-analysis [J]. EFORT Open Rev, 2024, 9(10): 953-968.
Cai G, Song X, Luo H, et al. NLRP3 blockade by MCC950 suppressed osteoclastogenesis via NF-κB/c-Fos/NFATc1 signal pathway and alleviated bone loss in diabetes mellitus [J]. Mol Cell Endocrinol, 2024, 594: 112382.
Tao L, Huang W, Li Z, et al. Transcriptome Analysis of Differentially Expressed Genes and Molecular Pathways Involved in C2C12 Cells Myogenic Differentiation [J]. Mol Biotechnol, 2024:
Ren Y, Tang H, Zhang L, et al. Exploration of therapeutic models for psycho-cardiology: From cardiac to psychological rehabilitation [J]. Heliyon, 2024, 10(6): e27484.
Lei X, Song X, Fan Y, et al. The Role and Potential Mechanism of Complement Factor D in Fibromyalgia Development [J]. J Pain Res, 2023, 16: 4337-4351.
Cheng X, Song X, Li Z, et al. Acyloxyacyl hydrolase deficiency induces chronic inflammation and bone loss in male mice [J]. J Mol Med (Berl), 2022, 100(11): 1599-1616.
个人荣誉及获奖:
入选台州市高层次人才特殊支持计划青年人才。
获WCO-IOF ESCEO世界骨质疏松大会——青年研究奖、浙江省医师协会骨质疏松与骨矿盐疾病专委会竞赛二等奖、恩泽医疗中心(集团)科技进步奖一等奖等荣誉或称号。